I-Feline N-terminal Pro-brain Natriuretic Peptide Quantitative Kit (Fluorescent Immunochromatography Assay of Rare Earth Nanocrystals) (fNT-proBNP)

[Igama lemveliso]

Igama: feline NT-proBNP inyathelo elinye uvavanyo

[Iinkcukacha zokuPakisha]

Iimvavanyo ezili-10/ibhokisi

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

Ukuqheleka

Ngethuba lokufihla, iprotheni inamathele kwi-BNP ye-physiologically esebenzayo (i-77th ukuya kwi-108th amino acids) kunye ne-n-terminal fragment NT-proBNP (i-1st ukuya kwi-76th amino acids).Xa i-BNP, eyi-32 i-amino acids ubude, ifihliwe egazini, ibophelela kwi-receptors yayo (NPRA kunye ne-NPRB) kwaye ilawula uxinzelelo lwegazi ngeendlela ezahlukeneyo.I-NT-proBNP, eyi-76 amino acids ubude, ayinayo umsebenzi we-biological, kodwa ngenxa yokuba inobomi obude kune-BNP, ifaneleke ngakumbi njengesalathisi sokufumanisa izifo zentliziyo ezahlukahlukeneyo.Kuvavanyo lweklinikhi yezilwanyana ezifuywayo, ukuxinwa kwegazi kwe-NT-proBNP kwizinja kuphezulu kune-900 pmol / L, kwaye iikati ziphezulu kune-270 pmol / L, kwaye kukho ingozi enkulu yezifo ezinxulumene nentliziyo.Nangona kunjalo, kufuneka kuqatshelwe ukuba ngenxa yokuba i-NT-proBNP ikhutshwe yizintso, xa isilwanyana sihlupheka ngenxa yezifo ezinxulumene nezintso, ukuxinwa kwe-NT-proBNP emzimbeni kuya kwanda kwaye ubuxoki buvela kuvavanyo.

Umgaqo-siseko wokufunyanwa

Le mveliso ithatha i-fluorescence immunochromatography ukuze ibone umxholo we-fNT-proBNP kwi-serum / plasma ngokobungakanani.Umgaqo osisiseko: Kukho imigca ye-T kunye ne-C kwi-nitric acid fiber membrane ngokulandelelana, kwaye umgca we-T uqatywe nge-antibody a eqaphela ngokukodwa i-fNT-proBNP.I-pad yokudibanisa ifafazwe ngenye i-fluorescent nanomaterial ebhalwe i-antibody b enokuchonga ngokuthe ngqo i-FDT-probNP.Kwisampuli, i-FDT-probNP idibanisa kuqala kunye ne-nanomaterial ebhalwe i-antibody b ukwenza i-complex, kwaye emva koko ukuya kwi-chromatography ephezulu, i-complex idibanisa kunye ne-T-line antibody A ukwenza isakhiwo sesandwich.Xa i-excitation ye-irradiation yokukhanya, i-nanomaterial ikhupha iimpawu ze-fluorescence.Amandla omqondiso ahambelana ngokufanelekileyo kunye nokuxinwa kwe-fNT-proBNP kwisampuli.

Ngaphambili: ICanine/Feline CystatinC Quantitative Kit (Fluorescent Immunochromatography Assay of Rare Earth Nanocrystals) (CysC)

Okulandelayo: I-Cholyglycine Quantitative Kit (Fluorescent Immunochromatography Assay of Rare Earth Nanocrystals) (CG)

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