I-Hangzhou iNew-Chatechnology Coutechnology Co., Ltd.Ngokusemthethweni wabhengeza ukumiselwa kweemveliso ezimbini zokuxilonga kwizilwanyana ezikwi-Inno-Quostistic ye-Glosostic: I-Canene / Sdma / SDMA / SDMA / i-CYSC / i-1 kunye ne-1), ezizisa isisombululo esitsha nesichazayo kwizihlomelo zezempilo zezilwanyana kunye nonyango.
Umzobo 1 Umsebenzi we-Canine ye-Canine Renal Chite
Umzobo 2 Feline Ranin Umsebenzi weKit yovavanyo kathathu
Ngo-Okthobha 2022, i-bie-biecal-bi biotechnology co., ltd.wayengowokuqala ukuqalisa i-Spee-Channel's Channel Isxy fluoresces i-Sunossey, i-NTIMM4 (isizukulwana sesibini isiya-i-Pannel. I-Canene yakutshanje / iFeline Renen Constia Syrical Trippia ihambelana neemodeli zombini.
Umzobo 3 Ntimm4
Umzobo 4 Ntimm2
Ukukhethekileyo kwimolekyuli encinci yokuqinisekisa uphando kunye nophuhliso lweminyaka emithandathu, iimveliso ezintsha zisungulwe.
Ukuchaneka kwemali encinci yemolekyuli bekusoloko kulucelomngeni ukoyiswa kwicandelo lovavanyo lwe-PCT, kwaye lukwindawo yophando olwenziwe kunye nophuhliso lwe-Bist olwenziweyo kwi-Bied kwi-6 eyadlulayo. Ukucima umzimba kunye nokubola kweempawu zezixhobo zemveli zemveli zichaphazela ngqo ukuchaneka kweziphumo zokuchongwa kwemolekyuli. Itekhnoloji ye-nanocrystal ye-nanocrystal, isizukulwana sesine se-Nanomascent Nanomasceccent Anomatials ephuhliswe ngovavanyo olutsha, liqwalaselwe njengezona zininzi zeFluorescent kwimarike, enesiphene sokukhanya okukhanyayo. Ukudityaniswa neminyaka eliqela yokuphumelela kwenkqubo, ekugqibeleni isombulule ingxaki yehlabathi lonke yokuchaneka okubi kuvavanyo lweemolekyuli. I-typeng yokuqala yindawo yokufumana ikhithi yovavanyo. Iqinisekisa ukuchaneka kweemolekyuli ezimbini ezincinci (i-creayininine & SDMA) I-Regegement Reagents kwixesha lokuqinisekiswa kweminyaka emi-2.
"Uvavanyo olunye lukhona, kutheni le nto ukuphuhlisa umsebenzi we-renal"Ibala lendawo yokuphuhlisa umsebenzi we-renal
Okwangoku, izikhombisi eziqhelekileyo zomsebenzi ongaqhelekanga kwizinja kunye neekati zibandakanya i-dianine (i-crea) kunye ne-UreaItrogen kwi-biochemistry; I-CYSC (i-cystatin c) kunye noRymmetlic Dimmethyligin (SDMA) kwizalathiso ezingagungqiyo, njalo. Xa i-glomerical filing incipha ngenxa yokulimala kwezintso, ezi zikhombisi ziya kuqokelela egazini kwaye zikhule kuxinzelelo, ngaloo ndlela zibonisa inqanaba le-renal-umsebenzi wokungakhathali. Umbutho wezizwe ngezizwe ukuba uphando lwezifo zezifo zezintso / i-DL; IBakala III, i-2.8-5.0.0 mg / i-IV yeBanga le-IV, iNqanaba:> 5.0 mg / dl).
Ukupheliswa kweRenal kwizinja kuhlelwe ngokwamanqanaba amane (iBanga i-IP, i-IT: 1.4-2.0 MG / DL: I-IV: Inqanaba lokuphelisa:> 4.0 mg / dl). Nangona kunjalo, ngenxa yovakalelo olulinganiselweyo lweLifine kwisifo sezifokazi esinganyangekiyo Ngokwedatha, i-SDMA inokubonisa ubungangamsha nge-25 ukuya kwi-40% yokupheliswa kweRenal, ngelixa i-deynine idla ngokuthathwa njengengaqhelekanga kwi-75% yokuphazamiseka.
I-CYSC (i-cystatin c) yi-cystine yothintelo, ubunzima obuphantsi (13.3 kd), protein ongesosiseko. Ngomnye wabamakisha abasetyenzisiweyo osetyenzisiweyo osetyenzisiweyo kwinqanaba le-Renal kwangoko. Njengokudalwa kunye ne-SDMA, ihlaselwe kwi-glosulus, kodwa yahlukile kwi-Detabolism kunye ne-SDMA ekubeni i-metabolism yayo ayisiyonto i-tetabold tubus.it yeyona nto iphambili Azange kuqatshelwe ngaphambili, ndikhokela abaninzi, iingcali kunye noncwadi kwizigqibo ezimbini ezahlukeneyo malunga nokulimala kwe-chysness ye-cysc Zilungelelanise kakuhle kwi-canine ye-canine, kodwa kakubi kwiikati.
Kutheni kukho izigqibo ezibini ezichaseneyo ezivela kwinye"Isalathiso somsebenzi we-Glomer "?
IsizathuI-Auria, eyona meko ixhaphakileyo Kwiikatikunokubain Ezinye iintlobo, ngakumbi kwiikati ezingamadoda. SIdatha ye-OME ibonisa ukuba imeko yeI-auriakwiikati ezingamadoda ukuphakama njenge-68.6%, kwaye uAnuriyaiya ngqoisiphumo sokuthintelaUkuncwina kwe-creatine,igaziUrea Nitrogen kunye ne-SDMA. TI-Erganism ihlala inyanzelekile kwaye ivelise i-creatine entsha,igaziI-Urea nitrogen ne-SDMA,Xa ubona bonkeizikhombisi ezintathu egaziningeli xesha, kuya kubakho ukonyuka okuthe tyaba okanye kuqhume kwizalathiso zezalathisoNokubaI-glimerulus is yonakele nyani.
I-cyscineIxabiso elikhethekileyoNgeli xesha, nangonaEsi salathisi siqinejiyiayifihli ngumchamo,it is ngokusebenzisa i-tubularye-reabjongela phantsi. NiniI-Anuria yenzekaKodwa umsebenzi weRenal yinto eqhelekileyo, i-CYSC Index isenokugcinwa kwinqanaba eliqhelekileyo. Kuphela xa i-glimerulusokanye ukonakaliswa kwe-tubular kwenzeka ngokwenyani,iI-cyscisalathisoiya kuphakanyiswato engaqhelekanga. Ke ngoko,Ukufunyanwa kwako konkeI-Index ezintathu zinakhoyenzaI-profayili echanekileyoosiskwaye unike unyango olufanayo ngokukhawuleza nangokufanelekileyo.
I-New-Viest Short Umsebenzi we-Renal COMHER DURCHER 3
UkucacisaImigaqo kunye neCownge iIimpawu zezalathiso,I-New-Viest Synal Umsebenzi wokuMakisha i-3-in-1 yeekhilomitha ze-1wereUzalelweibalulekileUkubaluleka kweKlinikhikubaIzinja kunye neekati (ngakumbi iikati)nge-anauria:
I-New-Viest Synal Umsebenzi wokuMakisha i-3-in-1 yeekhilomitha ze-1 zikhonaisetyenziselwa ukwahlula ukubaNantsi laphoUmsebenzi wokwenyani wokulimalaKwimeko ye-anuriaor iphumela kwiIbhloko yokuphakama kweekhonts ngenxa ye-Auria.Ukulimala kwe-Renal Umsebenzi weRenal kufuna kuphela umchamoI-Cathetatelization kwaye inxulumeneukhathalelo, kwaye iprognosis ingcono. IUkuphakanyiswa kokuphakanyiswa kwesalathisoayifuni kuphelaumbusoUkunyanzeliswa kunye nonyango lwe-anti-insulmatory, kodwa luhambelana nonyango ngesifo seRenal, kwaye iprognosisis inomdla, kwaye kunokwenzeka ukuba iguqukele kwisifo sezintso.
Apha ngezantsiiUmsebenzi omtsha weRenal marI-Ker 3-in-1kitsIdatha eqhelekileyoI-auria(Engafundangaukwenzakala kwezintso) kwayeI-auria+ Ukonzakala kwezikokuvavanyo olutshaiklinikiAmatyala ophando:
| I-Anuria ihlolisisiwe I-New-Viest Synal Umsebenzi wokuMakisha i-3-in-1 yeekhilomitha ze-1 | Iprojekthi | Isiphumo | Isiphumo |
| Ukulala | + | + | |
| I-SDMA | + | + | |
| I-cysc | + | - | |
| Ukuqukumbela | I-Auria ibangele ukwenzakala kwe-renal | Inqanaba lokuqala le-anauria kunye nokulimala i-renal okanye i-anuria engafiki ingozi ye-renal |
Apha ngezantsiInxalenye yeklinikhi eqhelekileyoIdatha kunye neNqanabakwiUmsebenzi omtsha-wovavanyokits:
| Ikati | Imbali yezonyango | Uphawu lweklinikhi | I-CYSC (MG / L) | Sdha (IG / DL) | Cr (mg / dl) | Ukuqukumbela |
| 202409090902 | I-cystitis / ukwenzakala kwe-reati | Imeko embi yengqondo, ilahle i-tettite, i-Abnal Index, i-Auria (i-Anuria (i-charnia (i-ornal engapheliyo, i-Auria) | 1.09 | I-86.47 | 8.18 | Ukwenzakala kwakhona nge-anuria |
| 2024091201 | / | Imeko embi yengqondo, i-Auria, umsebenzi weRenal yeRenal | 0.51 | 27.44 | 8.21 | Akukho monakalo ye-renal ene-anuria / inqanaba lokuqala |
| 2024092702 | / | I-auria | 0.31 | > I-100,00 | I-9.04 | Akukho monakalo ye-renal ene-anuria / inqanaba lokuqala |
| 2024103101 | / | I-auria | I-0.3 | 14.11 | 6.52 | Akukho monakalo ye-renal ene-anuria / inqanaba lokuqala |
| 2024112712 | I-auria | 0.5 | > I-100,00 | 8.85 | Akukho monakalo ye-renal ene-anuria / inqanaba lokuqala | |
| 2024112601 | I-DYSSIRIA / ANURIA | I-0.43 | > I-100,00 | I-9.06 | Akukho monakalo ye-renal ene-anuria / inqanaba lokuqala | |
| 0.47 | > I-100,00 | I-878 | Akukho monakalo ye-renal ene-anuria / inqanaba lokuqala | |||
| 2024112712 | / | I-auria | 0.54 | I-94.03 | 8.64 | Akukho monakalo ye-renal ene-anuria / inqanaba lokuqala |
Kwimeko ye-anauria, ngenxa yeUmahluko kwiiIndlela yangaphakathi ye-metabolickwi-Index nganye,Kuya kubangelwa kukho umahluko omkhuluI-renal efanayoumsebenziIsalathiso sokupholisa. Ke ngoko,Ukwahlulahlulwa kwesiqheloukwenzakala kwakhonaof Ukudalwa okanye i-SDMA ayisasebenzi, kwaye isiphelo sekliniki esikufutshane sinokufumaneka kuphela ngokudibanisa uhlaziyo kunye nesinye isikhombisi "cysc".II-T iyacetyiswa ukuba iilebhu zeelebhu (izibhedlele) ziseka ngaphakathiimigangathoNgokusekwe kumava osekliniki, ukuze kuphonononge ukubaluleka kweklinikhi entsha.
Ekugqibeleni, nI-EW-Veech BiotechIthembaukuba eli nqaku lizakwenzaphosa isitena ukutsala i-jade, kwaye unethemba lokubaIyeza le-gesti yezilwanyana zaseTshayinakwayeAbavelisi be-ReagenolociyaPhuhlisa iimveliso ezibalulekileyo zeklinikhi kwaye uncede oogqirha bezilwanyana zasekhaya ezingakumbi zokufikelela kwinqanaba eliphezulu emhlabeni!
ISIHLOMELO: Ukwamkelwa kwesicelo se-patent sokukhusela ubuchule bokukhusela
IXESHA LOKUQALA: Nge-12 kaFebruwari-12 ukuya ku-525
